- Causes of gynecomastia.

Causes of gynecomastia.
Gynecomastia.

• Genetic : klinefelter syndrome.


• Young boy (puberty): due to transient increase of plasma estradiol.


• Neonate: due to persistent maternal or placental lactogens.


• Estrogen and estrogen like drugs (e.g. digitalis).


• Cirrohosis,Cimetidine,Cytotoxic drugs.


• Old age(due to conversion of androgen to estrogen in extra glandular tissue),Overactive thyroid (Hyperthyroidism)


• Myxedema,Marijuana.


• Acromrgally.


• Spironolactone,Steroids.


• Tumour (e.g. testis,adrenal,bronchogenic carcinoma).


• INH,Iron deposition in testis.


• Alcoholism.